Benerva 300 mg - vitamin b1 deficiencies -20 tablets

Product Description

Vitamin B1-based drug useful in cases of severe deficiencies.

Indications

Benerva 300 mg is indicated in the prophylaxis and treatment of vitamin B1 deficiency due to increased demand or reduced absorption (beriberi and its various clinical forms). Deficiency polyneuritis (alcoholic). Cardiac myopathy in alcoholics. At high doses, adjuvant therapy for non-deficiency neuritis and polyneuritis.

Composition

Active ingredients

One tablet contains: thiamine hydrochloride (vitamin B1) 300 mg.

Excipients

One tablet contains: talc, povidone K90, magnesium stearate, methacrylic acid – ethyl acrylate copolymer (1:1), macrogol 6000, sodium carmellose.

Directions for use and Dosage

NB: Benerva tablets at a high dosage (300 mg) allow for intensive treatment and should be used only for the most serious cases and only under medical supervision.

600–1200 mg (2–4 Benerva 300 mg tablets) per day for 1–2 weeks, then 300 mg (1 Benerva 300 mg tablet) per day for more than 2 weeks. weeks.

Warnings

Preparations based on vitamin B1 or derivatives, especially when administered parenterally, may cause problems in subjects who have had sensitization phenomena or allergic reactions. The risk of hypersensitivity reactions is increased with repeated intramuscular administration. Oral administration is therefore preferable, where possible.

Do not exceed the recommended dose. Very high doses of some components, in particular Vitamin A, Vitamin D, iron and copper, may be harmful to health. Patients taking other mono- or multivitamin preparations or any other medicines or who are undergoing medical treatment should consult a doctor before taking this medicine.

This medicine should be taken with particular caution together with any other product, including supplements and/or fortified foods/drinks, containing Vitamin A, or beta-carotene, since they may be harmful to the body. High doses of these compounds may harm the fetus and cause hypervitaminosis A.

This medicine should be taken with particular caution together with any other product, including supplements and/or fortified foods/drinks, containing Vitamin D since high daily doses of this compound may cause hypervitaminosis D.

Patients with nephrolithiasis or urolithiasis should be careful when using vitamin supplements since calcium, ascorbic acid and Vitamin D may influence stone formation.

Contraindications

Known hypersensitivity to the active substance or to any of the excipients.

Interactions

Thiosemicarbazone and 5-fluorouracil inhibit the activity of thiamine. Interference with laboratory tests:

• Vitamin B1 may give false positive results in the determination of urobilinogen with the Ehrlich reagent;
• High doses of vitamin B1 may interfere with the spectrophotometric determination of serum theophylline.

Undesirable effects

NB: the undesirable effects listed below derive from spontaneous reports and it is therefore not possible to classify them by frequency categories. 

Immune system disorders: In individual cases, allergic and anaphylactic reactions have been reported, with symptoms such as pruritus, urticaria, angioedema, abdominal pain, difficulty breathing, tachycardia, palpitations and shock. 

Gastrointestinal disorders: Mild gastrointestinal disorders such as nausea, vomiting, diarrhoea and abdominal pain have been reported.

Overdose

No adverse reactions have been reported. Overdose reported

Pregnancy and breastfeeding

This product is not indicated for use during pregnancy or breastfeeding.

Format

20 tablets