Guttalax 7,5 mg/ml - helps with occasional constipation oral drops 15 ml

Product Description

Drops

Active ingredients
1 ml (15 drops) of solution contains: sodium picosulfate 7.5 mg.

Excipients
Sodium benzoate, liquid sorbitol, sodium citrate, citric acid monohydrate, purified water.

Indications
Short-term treatment of occasional constipation.

Contraindications/side effects
Hypersensitivity to the active substance and to any of the excipients. Acute or unknown abdominal pain, nausea or vomiting, intestinal or biliary tract obstruction or stenosis, paralytic ileus, acute inflammation of the gastrointestinal tract, rectal bleeding of unknown origin, severe dehydration, gallstones, liver failure. Pregnancy and breastfeeding. The medicine is contraindicated in patients with acute abdominal conditions such as appendicitis and severe abdominal pain associated with nausea and vomiting, which may be indicative of the serious conditions listed above. The product is also contraindicated in patients with known hypersensitivity to sodium picosulfate (active ingredient) or any other component of the product (excipients). Do not administer to children under 3 years of age. Pediatrics. In case of rare hereditary conditions of incompatibility with one of the excipients, the use of the medicine is contraindicated.

Dosage
In adults, it is recommended to start with 7-8 drops in water and reduce if the effect is excessive or increase if the laxative effect is not achieved. In cases of obstinate constipation, up to 15-20 drops in water can be used. In children (over 3 years): 2-3 drops in water. The medicine should preferably be taken in the evening to induce evacuation the following morning. Swallow with an adequate amount of water. A diet rich in liquids promotes the effect of the medicine. Do not exceed the recommended dose. The correct dose is the minimum sufficient to produce easy evacuation of soft stools. It is advisable to initially use the minimum recommended doses. When necessary, the dose can then be increased, but never exceed the maximum indicated. Laxatives should be used as infrequently as possible and for no more than seven days. Use for longer periods requires a doctor's prescription after adequate evaluation of the individual case.

Storage
No special storage precautions. Shelf life after first opening: 12 months.

Warnings
Do not take continuously every day or for long periods of time without investigating the cause of constipation. Prolonged and excessive use may lead to diarrhea, electrolyte imbalance, and hypokalemia. Cases of dizziness and/or syncope have been reported in patients taking the drug. Available data on these cases suggest that the events may be related to defecation syncope (or syncope attributable to straining to defecate), or to a vasovagal response to abdominal pain related to constipation, and not necessarily to the intake of sodium picosulfate itself. Laxative abuse (frequent or prolonged use, or excessive doses) can cause persistent diarrhea, resulting in loss of water, minerals (especially potassium), and other essential nutrients. In more severe cases, dehydration or hypokalemia may occur, which can lead to cardiac or neuromuscular dysfunction, especially when concomitantly treated with cardiac glycosides, diuretics, or corticosteroids. Laxative abuse, especially contact laxatives (stimulant laxatives), can cause dependence (and thus the possible need to gradually increase the dosage), chronic constipation, and loss of normal intestinal function (intestinal atony). In children between the ages of 3 and 12, the medicine should be used only after consulting a doctor. Treatment of chronic or recurrent constipation always requires medical intervention for diagnosis, prescription of medications, and monitoring during therapy. Consult your doctor when the need for a laxative arises from a sudden change in previous bowel habits that lasts more than two weeks or when the use of the laxative fails to produce any effect. It is also advisable for elderly or otherwise unhealthy subjects to consult their doctor before using the medicine. 1 ml (15 drops) of solution contains 0.45 g of sorbitol, equivalent to 0.6 g of sorbitol for the maximum recommended daily dose in adults. Patients with rare hereditary conditions of fructose intolerance should not take this medicine.

Interactions
Laxatives can reduce the residence time in the intestine, and therefore the absorption, of other drugs administered orally at the same time. Therefore, avoid taking laxatives and other medications at the same time: after taking a medicine, wait at least 2 hours before taking the laxative. Milk or antacids can alter the effect of the medicine; Leave an interval of at least one hour before taking the laxative. Continued use may increase the patient's response to oral anticoagulants and alter glucose tolerance. Concomitant use of diuretics or adrenocorticosteroids and excessive doses may lead to an increased risk of electrolyte imbalance. This imbalance, in turn, may lead to increased sensitivity to cardiac glycosides. Concomitant administration of antibiotics may reduce the laxative effect.

Undesirable effects
Frequencies of undesirable effects: very common >= 1/10; common >= 1/100, < 1/10; uncommon >= 1/1,000, < 1/100; rare >= 1/10,000, < 1/1,000; very rare < 1/10,000; not known. Immune system disorders. Not known: hypersensitivity, angioneurotic edema, and skin reactions. Nervous system disorders. Uncommon: dizziness; not known: syncope. The phenomena of dizziness and syncope that occur after taking sodium picosulfate seem to be attributable to a vasovagal response (following, for example, abdominal pain or stool evacuation). Gastrointestinal disorders. Very common: diarrhoea; common: abdominal cramps, abdominal pain, and abdominal discomfort; uncommon: vomiting, nausea. Occasionally: isolated cramping pain or abdominal colic, more frequent in cases of severe constipation.

Pregnancy and breastfeeding
No studies have been conducted to evaluate the effects on human fertility. Non-clinical studies have not revealed any effects on fertility. There are no adequate and well-controlled studies on the use of the medicinal product during pregnancy. Long-term experience has shown no evidence of adverse or harmful effects during pregnancy. Although no toxic effects have ever been reported during pregnancy, the medicine should be used only when necessary, under the direct supervision of a doctor, after weighing the expected benefit to the mother against the possible risk to the fetus. Clinical data demonstrate that neither the active fraction of sodium picosulfate, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), nor the conjugated form (its glucuronic derivatives), are excreted in detectable quantities in breast milk. However, the medicine should be used only when necessary, under the direct supervision of a doctor, after weighing the expected benefit to the mother against the possible risk to the infant.