Treatment and prevention of tick, flea, and lice infestations.
Indications
Spot on is a treatment against tick infestations (Rhipicephalus spp., Dermacentor spp., Boophilus spp.), fleas (Ctenocephalides spp.), and lice in adult dogs and puppies. Fipronil acts rapidly with lethal action on ticks, preventing the development of the parasite and the transmission of any infections the tick may carry. It is effective against the main tick species present in Italy, including Ixodes ricinus, which is responsible for the transmission of Lyme disease to dogs, cats, and humans. Fipronil acts on fleas, rapidly killing adult fleas and preventing egg laying, thus avoiding new infestations. Thanks to its lethal effect on adult fleas, fipronil effectively helps control and resolve Flea Allergy Dermatitis (FAD), which in dogs is caused by the sensitizing action of antigens contained in the saliva of these parasites. Furthermore, with a single treatment, fipronil quickly and permanently controls and resolves lice infestations, particularly those caused by Trichodectes canis, the dog chewing louse. Fipronil eliminates fleas within 24 hours and ticks and lice within 48 hours of infestation.
Directions for Use and Dosage
One 1.34 ml single-dose pipette for dogs weighing 10 to 20 kg, corresponding to the minimum recommended dose of 6.7 mg/kg of fipronil. A single application of the product protects the animal from new tick, flea, and lice infestations, in particular:
- from ticks: up to 1 month after treatment;
- from fleas: up to 3 months after treatment.
Route of administration
External use: for direct skin application.
Directions for use
- Break the pre-cut end of the pipette;
- Apply the product to the skin between the shoulder blades, an area where the dog cannot lick itself, avoiding the product from being transferred. The pipette should be applied directly to the skin, not the fur;
- Press the sides of the pipette until it is completely empty (as shown in the illustrations). Fipronil diffuses into the epidermis, concentrating in the sebaceous glands of hair follicles within 24 hours of application.
Warnings
Special warnings
It is important to apply the product to an area where the animal cannot lick it, and to ensure that animals do not lick each other after treatment. Avoid contact with the animal's eyes. In case of accidental contact with the eyes, rinse immediately with plenty of water. Do not apply the product to wounds or broken skin.
Precautions
It is recommended to avoid immersion in water or bathing for 2 days after application of the product, and bathing more frequently than once a week, as there is no data available to demonstrate how this affects the product's activity. Emollient shampoos can be used before treatment, but if used weekly after application of the product, they reduce the duration of flea protection to approximately 5 weeks. Weekly bathing with medicated shampoos containing 2% chlorhexidine did not reduce the product's effectiveness against fleas in a 6-week study. It is recommended that dogs not be allowed to bathe in watercourses for 2 days after application of the product.
If the dog was treated before exposure to ticks, the ticks will be eliminated within the first 24-48 hours after the attack, i.e. before the dog finishes feeding, reducing but not eliminating the risk of disease transmission. Once dead, the ticks will fall off the animals; any remaining ticks can be easily removed by gently pulling them. For proper edoparasitic prevention, monthly treatments are recommended during peak seasonal periods.
Side Effects
If animals lick themselves, transient hypersalivation may be observed, mainly due to the product's excipients. Among the extremely rare suspected adverse reactions, transient skin reactions at the application site (skin discoloration, local alopecia, itching, erythema) and widespread itching or alopecia after application have been described.
Exceptionally, hypersalivation, reversible neurological symptoms (peresthesia, depression, nervous symptoms), vomiting, or respiratory symptoms have been observed. If you experience any serious adverse reactions or other reactions not mentioned in this package insert, please inform your veterinarian.
Overdose
In safety studies, no adverse effects were observed in 8-week-old puppies, growing dogs, and dogs weighing approximately 2 kg, treated once at doses five times the recommended dose. The risk of adverse reactions (see Adverse Reactions section) may, however, increase in the event of an overdose, so animals should always be treated with the pipette of the size corresponding to their weight. Do not exceed the recommended dose.
Precautions to be taken by the person administering the product to animals
The product may cause irritation to mucous membranes and eyes. It is therefore recommended to avoid contact with mouth and eyes. In case of accidental contact, rinse immediately with plenty of water. If eye irritation persists, consult a doctor and show the label.
Avoid contact with FRONTLINE SPOT ON DOGS by animals or people with known sensitivity to insecticides or alcohol. Avoid contact of the contents with hands; if this occurs, wash your hands with
soap and water. Wash your hands after use. Do not touch animals or allow children to play with treated animals until the application site is dry. It is therefore recommended not to treat animals during the heat of the day, but to treat them in the evening and, if recently treated, not to allow them to sleep with their owners, especially children. Do not smoke, drink, or eat during application.
Format
3 pipettes
Product Code:FRCM221033
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