Supartz - joint function intra-articular syringe 2.5 ml

Product Description

Medical device for joint function

Indications

Supartz is indicated for the treatment of knee osteoarthritis and shoulder periarthritis.

A sterile, non-pyrogenic, highly purified, non-inflammatory, high molecular weight sodium hyaluronate solution extracted from rooster combs is a polysaccharide containing repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine.

Sodium hyaluronate is a common component of all extracellular matrices of connective tissues. It is found in many different species, including humans, but is chemically identical regardless of the species of origin. The sodium hyaluronate used in the manufacture of Supartz is of avian origin and is derived through a prolonged purification process.

Supartz is a clear, odorless solution with a pH of 6.8 to 7.8 and an osmotic pressure-to-saline ratio of 1.0 to 1.2. After injection into the joint, a small amount of Supartz is metabolized in the synovial fluid, while the remainder is distributed throughout the synovial tissues where it is partially degraded into smaller molecules.

Supartz then enters the bloodstream and is metabolized primarily in the liver. The products of metabolism are non-toxic and are eliminated from the body through the lungs, intestines, and urinary tract. Supartz is marketed as a sterile solution in pre-filled disposable syringes to reduce the risk of contamination during aspiration of the solution.

Directions for use and Dosage

The recommended treatment regimen for supartz in adults consists of five (5) injections into the knee joint cavity or shoulder joint (joint cavity, subacromial bursa, and biceps tendon sheath), at intervals of one weekly. However, it may be necessary to synchronize the timing of the intra-articular injection with the patient's symptoms.

• If symptoms do not improve, discontinue administration of supartz after five (5) injections.

• Before injecting supartz, remove the effusion, if present, by arthrocentesis.

• Since supartz is viscous, use needles of the appropriate size for injections (e.g. size 22-23).

Format

1 pre-filled syringe 2.5 ml