Reactine antihistamine 14 tablets 5 mg + 120 mg rp

Product Description

Reactine is indicated for the short-term symptomatic treatment of seasonal and/or perennial allergic rhinitis with nasal congestion and hypersecretion, nasal and/or ocular itching, sneezing, and tearing. Due to the pharmacokinetic, pharmacodynamic, and tolerability profile of cetirizine, no interactions with this antihistamine are expected. In fact, no significant pharmacodynamic or pharmacokinetic interactions have been reported in drug-drug interaction studies conducted, in particular, with pseudoephedrine or theophylline (400 mg/day). The activity of sympathomimetic amines such as pseudoephedrine contained in this drug is increased by the concomitant administration of monoamine oxidase inhibitors and beta-blockers. Due to the long duration of action of monoamine oxidase inhibitors, the activity of sympathomimetic amines can be observed even 15 days after discontinuation of administration. Sympathomimetic amines reduce the antihypertensive effects of methyldopa, guanethidine, and reserpine. Administration of pseudoephedrine to digitalized patients increases ectopic myocardial activity. Antacids increase the absorption of pseudoephedrine, while concomitant intake of kaolin reduces it. The extent of cetirizine absorption is not reduced by food intake, although the rate of absorption is decreased.

Composition: One tablet contains 5 mg cetirizine dihydrochloride and 120 mg pseudoephedrine hydrochloride.