Salicylic acid 5% ointment - treatment of psoriasis, acne, seborrhea, eczema 30 g

Product Description

Treatment of psoriasis, acne vulgaris, seborrhea in adults and children.

Indications

Removal of warts and calluses in adults and children, Local treatment of some forms of eczema and ichthyosis in adults.

Composition

Active ingredients

Marco Viti salicylic acid 2% ointment 100 g of ointment contain Active ingredient: salicylic acid 2 g.
Marco Viti salicylic acid 5% ointment 100 g of ointment contain Active ingredient: salicylic acid 5 g.
Marco Viti Salicylic Acid 10% Ointment 100 g of ointment contain Active ingredient: salicylic acid 10 g.

Excipients

White petrolatum.

Directions for use and Dosage

Apply the smallest amount of ointment locally in relation to the area to be treated with a light massage. Start treatment by applying the medicine only to a small portion of skin or only once a day, so as not to irritate the skin.

Warnings

The medicine must not be swallowed. Salicylic acid is irritating and may cause dermatitis (see section 4.8). When treating calluses and warts, the surrounding intact skin must be protected to minimize absorption of the active ingredient. Salicylic acid should not be used for long periods of time, at high concentrations, on large areas of the body, or on broken or inflamed skin, as excessive absorption of the active ingredient can cause systemic salicylate poisoning (see section 4.9), primarily in children, which can be fatal. Avoid contact with the mouth, eyes, genitals, and other mucous membranes. Use with caution in children as experience with the use of salicylic acid in this population is limited. Improvement of the treated skin may be observed after 6 weeks of therapy or after 12 weeks in case of removal of a wart.

Contraindications

Hypersensitivity to the active substance, to salicylates or to any of the excipients (patients hypersensitive to salicylates, such as acetylsalicylic acid, propyl salicylate, bromosalicylic acid, zinc salicylate, may also be hypersensitive to salicylic acid), - children under 2 years of age, - diabetes - peripheral vascular disease.

Interactions

Salicylic acid may interact with the following medicines: - Coumarin anticoagulants (acenocoumarol, dicoumarol, phenprocoumon, and warfarin) and 1,3-hydandione derivatives (anisindione, phenidione), as salicylic acid may inhibit platelet aggregation and displace them from their binding site with plasma proteins, thus causing an increased risk of bleeding. - Inhibitors of coagulation-activated factor X (heparins and heparinoids), as in case of neuraxial anesthesia (spinal or epidural), the concomitant use of salicylic acid may cause a rapid increase in the risk of bleeding and hematoma. - Glyburide, as excessive hypoglycemia may occur by an unknown mechanism. - Probenecid, as salicylic acid may increase the risk of bleeding and hematoma. cause the uricosuric effects of this drug to be reversed. - Acetazolamide, as this may increase the side effects of salicylate. - Varicella vaccine, as salicylic acid may increase the risk of developing Reye's syndrome. Furthermore, salicylic acid should not be used concomitantly with tamarind (a tropical tree belonging to the Fabaceae family) and Salvia miltiorrhiza or Tan-Shen (a plant of the Labiateae family), as this may result in a rapid increase in plasma salicylate levels, resulting in increased toxicity.

Undesirable effects

The following are the undesirable effects of salicylic acid, organized according to the MedDRA systemic classification. There are insufficient data to determine the frequency of the individual effects listed. Metabolism and nutrition disorders Hypoglycemia. Skin and subcutaneous tissue disorders: Irritation, dermatitis, burning, itching, erythema, skin peeling, facial scarring.

Overdose

No cases of overdose from locally applied salicylic acid have been reported. However, if the active ingredient is excessively absorbed (e.g., prolonged application over large areas of the body or on damaged and inflamed skin), salicylicism may occur. Symptoms of salicylicism include nausea, vomiting, tinnitus, and dizziness. Rarely, gastric ulcers, asthma, hepatotoxicity, renal failure, and pancreatic toxicity may occur.

Pregnancy and breastfeeding

There are no adequate data regarding the use of salicylic acid in pregnant and breastfeeding women. Therefore, salicylic acid solutions and ointments should not be used during pregnancy and breastfeeding unless clearly necessary. Studies in animals have shown reproductive toxicity (see section 5.3). The potential risk for humans is unknown. However, it should be considered that despite being used topically, salicylic acid is absorbed systemically, easily crosses the placenta, being found in higher concentrations in fetal plasma, and is excreted in breast milk.

Format

30 g