Bayer italia Advantix spot on for dogs from 10 to 25 kg - 6 pipettes x 2,5 ml

Product Description

Veterinary drug for the treatment and prevention of fleas in dogs weighing 10 to 25 kg.

Indications

Advantix Spot On for dogs weighing 10 to 25 kg from Bayer is a veterinary drug for the treatment and prevention of flea infestations (Ctenocephalides canis, Ctenocephalides felis). Fleas on dogs are killed within one day of treatment, and one treatment prevents further flea infestation for four weeks. The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD). For the treatment of lice (Trichod ectes canis). The product has persistent acaricidal and repellent efficacy against tick infestations (Rhipicephalus sanguineus and Ixodes ricinus for four weeks, and Dermacentor reticulatus for three weeks). Through its repellent and knockdown action on the Rhipicephalus sanguineus tick vector, the product reduces the likelihood of transmission of the Ehrlichia canis pathogen, thereby reducing the risk of canine ehrlichiosis. The risk reduction was demonstrated in studies starting from the third day after product application and persists for four weeks. Ticks already present on the dog may not be killed within two days after treatment and may remain attached and visible. It is therefore recommended to remove any ticks already present on the dog at the time of treatment to prevent them from attaching and taking a blood meal. One treatment provides repellent (anti-feeding) activity against sand flies (Phlebotomus papatasi for two weeks and Phlebotomus pernic iosus for three weeks), against mosquitoes (Aedes aegypti for two weeks and Culex pipiens for four weeks) and against horse flies (Stomoxys calcitrans) for four weeks.

Composition

Active ingredients

Each 2.5 ml pipette contains: Imidacloprid: 250.0 mg; permethrin (4 0/60): 1250.0 mg.
Excipient(s): Butylhydroxytoluene (E321): 2.5 mg

Excipients

Butylhydroxytoluene (E321), N-methylpyrrolidone, Miglyol 812, Citric acid (E330).

Directions for use and Dosage

The minimum recommended dose is: 10 mg/kg body weight (bw) of imidacloprid and 50 mg/kg body weight (bw) of permethrin.

To reduce reinfestation due to the appearance of new fleas, it is recommended to treat all dogs in the household. Other animals living in the same household should be treated with a suitable product. To further help reduce the environmental threat, the additional use of a suitable environmental treatment against adult fleas and their developing stages is recommended.

The product remains effective if the animal gets wet. However, intense and prolonged exposure to water should be avoided. In case of frequent exposure to water, the persistence of efficacy may be reduced. In these cases, do not repeat the treatment more frequently than once a week. If your dog requires shampooing, it is best to do so before applying Advantix or at least two weeks after application to optimize the product's effectiveness.

In case of lice infestation, a further veterinary visit is recommended 30 days after treatment, as some animals may require a second treatment.

To protect a dog throughout the sandfly season, treatment must be continued as directed throughout.

For cutaneous use only. Apply only to intact skin.

Warnings

Single ticks may attach or individual sandflies or mosquitoes may bite. For this reason, if conditions are unfavorable, treatment should not be continued. completely exclude the transmission of infectious diseases by these parasites. It is recommended to apply the treatment at least 3 days before expected exposure to E. canis. Regarding E. canis, studies have demonstrated a reduced risk of canine ehrlichiosis in dogs exposed to Rhipicephalus sanguineus ticks infected with E. canis from 3 days following application of the product and persisting for 4 weeks.

Special precautions for use in animals: Care should be taken to avoid contact of the contents of the pipette with the eyes or mouth of treated dogs. In particular, oral ingestion due to licking of the application site by treated animals or by animals in contact with them should be avoided. Do not use on cats. This product is extremely toxic to cats and could be fatal due to the unique physiology of cats, which are unable to metabolize certain compounds, including permethrin. To prevent cats from being accidentally exposed to the product, keep treated dogs away from cats after treatment and until the application site is dry. It is important to ensure that cats do not lick the application site of a dog treated with this product. If this occurs, seek immediate veterinary advice. Consult your veterinarian before using the product on sick and debilitated dogs.

Special precautions to be taken by the person administering the veterinary medicinal product to animals:

Avoid contact of the product with the skin, eyes, or mouth. Do not eat, drink, or smoke during application. Wash hands thoroughly after use. In case of accidental spillage on the skin, wash immediately with soap and water. People with known skin sensitivity may be particularly sensitive to this product. The predominant clinical symptoms, which may occur in extremely rare cases, are transient sensory irritation of the skin such as tingling, burning, or numbness. If the product accidentally gets into the eyes, rinse them thoroughly with water. If skin or eye irritation persists, seek medical advice immediately and show the package leaflet or label. Do not swallow. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or label. Treated dogs should not be handled, especially by children, until the application site is dry. This can be ensured, for example, by treating dogs in the evening. Recently treated dogs should not be allowed to sleep with their owners, especially children. To prevent children from having access to the pipettes, keep the pipette in the original packaging until ready for use and dispose of used pipettes immediately.

Other precautions: Since the product is dangerous for aquatic organisms, under no circumstances should treated dogs be allowed to enter any type of surface water for at least 48 hours after treatment. The solvent contained in Advantix Spot-on may stain some materials, including leather, fabric, plastic, and polished surfaces. Allow the application site to dry before allowing contact with such materials. No adverse clinical signs were observed in puppies or healthy adult dogs exposed to a 5x overdose, or in puppies whose mothers were treated with a 3x overdose of the product. Major incompatibilities: None known.

Contraindications

In the absence of available data, the product should not be used on puppies under 7 weeks of age or weighing less than 40 kg. Do not use in cases of hypersensitivity to the active substances or to any of the excipients. Do not use on cats.

Side effects

On very rare occasions, dogs may experience transient skin sensitivity (increased local itching, scratching and rubbing, hair loss and redness at the application site) or lethargy, which generally resolve spontaneously. In very rare cases, dogs may show behavioral changes (agitation, restlessness, whining or rolling movements), gastrointestinal symptoms (vomiting, diarrhea, hypersalivation, decreased appetite), and neurological signs such as staggering and twitching in dogs sensitive to permethrin. These signs are generally transient and resolve spontaneously. Poisoning in dogs following inadvertent oral ingestion is unlikely, although this may occur in very rare cases. If this occurs, neurological signs such as tremors and lethargy may occur. Treatment should be symptomatic. There is no known specific antidote. The frequency of adverse reactions is defined using the following conventions: very common (more than 1 in 10 animals treated displaying adverse reactions); common (more than 1 but less than 10 animals in 100 animals treated); uncommon (more than 1 but less than 10 animals in 1,000 animals treated); rare (more than 1 but less than 10 animals in 10,000 animals treated, including isolated reports).

Pregnancy and lactation

Can be used during pregnancy and lactation.

Storage

Do not freeze. After opening the foil pouch, store in a dry place at a temperature not exceeding 30 degrees C. Shelf life of the product in the foil pouch: 3 years. Shelf life of the product after opening the foil pouch: 12 months (all pipettes must be used within 12 months after opening the foil pouch or before the expiry date printed on the pipette, whichever is shorter). Shelf life of the opened pipette: After opening, the entire contents of the pipette must be applied to the animal's skin.

Format

6 Pipettes of 2.5 ml