Tachipirina children 250 mg - antipyretic analgesic 10 suppositories

Product Description

An analgesic and antipyretic drug for children, based on paracetamol, useful in cases of fever and pain of various kinds.

Indications

Tachipirina suppositories 250 mg is a drug administered to lower fever in children or to treat mild pain conditions including: headaches; myalgia; neuralgia. Tachipirina suppositories for children can be used in children. be used as an antipyretic in the treatment of symptoms related to feverish conditions in cases of influenza, respiratory conditions and exanthematous diseases.

Tachipirina suppositories for children: dosage

The dosage depends on the child's age and weight.

Children weighing between 11 and 12 kg (approximately between 18 and 24 months): 1 suppository at a time, to be repeated if necessary after 8 hours, without exceeding 3 administrations per day.

Children weighing between 13 and 20 kg (approximately between 2 and 7 years): 1 suppository at a time, to be repeated if necessary after 6 hours, without exceeding 4 administrations per day.

The need for treatments for more than 3 consecutive days must be assessed by the pediatrician.

Composition

Active ingredient: paracetamol 250 mg.
Excipients: solid semi-synthetic glycerides.

Warnings and precautions

In rare cases of allergic reactions, administration must be suspended and appropriate treatment must be initiated.
Use with caution in cases of chronic malnutrition (low hepatic glutathione reserves), dehydration, hypovolemia.
Paracetamol should be administered with caution to patients with mild to moderate hepatocellular insufficiency (including Gilbert's syndrome), severe hepatic insufficiency (Child-Pugh>9), acute hepatitis, concomitant treatment with drugs that alter liver function, glucose-6-phosphate dehydrogenase deficiency, haemolytic anaemia.
High or prolonged doses of the product can cause kidney and blood disorders, even serious ones. Therefore, administration to patients with renal insufficiency should be performed only if truly necessary and under direct medical supervision. In case of prolonged use, it is advisable to monitor liver and kidney function and blood count.
During treatment with paracetamol, before taking any other medication, check that it does not contain the same active ingredient, since if paracetamol is taken in high doses, serious adverse reactions can occur. Contact your doctor before combining any other medication.

Interactions

Concomitant use of paracetamol and chloramphenicol can increase the half-life of chloramphenicol, with the risk of increasing its toxicity. Concomitant use of paracetamol (4 g per day for at least 4 days) with oral anticoagulants can increase the half-life of chloramphenicol. may induce slight variations in INR values. In these cases, more frequent monitoring of INR values ​​should be conducted during concomitant use and after its discontinuation. Use with extreme caution and under close supervision during chronic treatment with drugs that can determine the induction of hepatic monooxygenases or in case of exposure to substances that can have this effect (for example, rifampicin, cimetidine, antiepileptics such as glutethimide, phenobarbital, carbamazepine). The same applies in cases of alcoholism and in patients treated with zidovudine. The administration of paracetamol may interfere with the determination of uric acid (by the phosphotungstic acid method) and with that of glycaemia (by the glucose-oxidase-peroxidase method).

Contraindications

• Hypersensitivity to the active substance or to any of the excipients.
• Patients with severe haemolytic anaemia (this contraindication does not apply to the 500 mg oral formulations).
• Severe hepatocellular insufficiency (this contraindication does not apply to the 500 mg oral formulations).

Undesirable effects

The following are the adverse reactions of paracetamol organised according to the MedDRA system organ classification. There are insufficient data to establish the frequency of the individual effects listed.

Blood and lymphatic system disorders: Thrombocytopenia, leukopenia, anaemia, agranulocytosis.
Immune system disorders: Hypersensitivity reactions (urticaria, laryngeal edema, angioedema, anaphylactic shock).
Nervous system disorders: Dizziness.
Gastrointestinal disorders: Gastrointestinal reaction.
Hepatobiliary disorders: Abnormal liver function, hepatitis.
Skin and subcutaneous tissue disorders: Erythema multiforme, Stevens-Johnson syndrome, epidermal necrolysis, rash.
Renal and urinary disorders: Acute renal failure, interstitial nephritis, haematuria, anuria.

Furthermore, very rare cases of serious skin reactions have been reported.

Format

Pack containing 10 Tachipirina 250 mg suppositories